【 Seminar Announcement 】
----------------------------------------
Date: Jan. 25 (Fri), 2013
Time: 16:00-17:30
Place: Seminar room (3rd floor) in Nanobiology building, Suita Campus
----------------------------------------
Title: "CMOS-based microelectrode arrays for in-vitro electrophysiology at high patiotemporal resolution"
Dr. Urs Frey
(RIKEN Quantitative Biology Center)
----- Abstract -----------------------------------------------
Microelectrode arrays (MEA) allow extracellular recording and stimulation from in-vitro preparations, such as cultured neuronal networks, retina, acute and cultured brain slices and more. Complementary metal-oxide-semiconductor (CMOS) is widely used to construct integrated circuits. This technology can be used to fabricate high-resolution MEA devices. I will present existing CMOS-based MEA systems, recent technology advancements and obtained electrophysiological recordings. An advantage of using CMOS technology for MEA is increased component connectivity, which allows to address a large number of microelectrodes on a small area, resulting in the ability to record and stimulate at high spatiotemporal resolution. As an example, this allows tracking of action potentials propagating on single axons. It also allows to drastically improve performance in spike sorting, making it possible to record and stimulate at single cell resolution and full population coverage in small neuronal networks.
--------------------------------------------------------------
世話人■大阪大学大学院生命機能研究科 細胞分子神経生物学研究室
教授 山本 亘彦
Ｅ-ｍａｉｌ：nobuhiko@fbs.osaka-u.ac.jp
Tel:06-6879-4636
----------------------------------------
Date: Jan. 25 (Fri), 2013
Time: 16:00-17:30
Place: Seminar room (3rd floor) in Nanobiology building, Suita Campus
----------------------------------------
Title: "CMOS-based microelectrode arrays for in-vitro electrophysiology at high patiotemporal resolution"
Dr. Urs Frey
(RIKEN Quantitative Biology Center)
----- Abstract -----------------------------------------------
Microelectrode arrays (MEA) allow extracellular recording and stimulation from in-vitro preparations, such as cultured neuronal networks, retina, acute and cultured brain slices and more. Complementary metal-oxide-semiconductor (CMOS) is widely used to construct integrated circuits. This technology can be used to fabricate high-resolution MEA devices. I will present existing CMOS-based MEA systems, recent technology advancements and obtained electrophysiological recordings. An advantage of using CMOS technology for MEA is increased component connectivity, which allows to address a large number of microelectrodes on a small area, resulting in the ability to record and stimulate at high spatiotemporal resolution. As an example, this allows tracking of action potentials propagating on single axons. It also allows to drastically improve performance in spike sorting, making it possible to record and stimulate at single cell resolution and full population coverage in small neuronal networks.
--------------------------------------------------------------
世話人■大阪大学大学院生命機能研究科 細胞分子神経生物学研究室
教授 山本 亘彦
Ｅ-ｍａｉｌ：nobuhiko@fbs.osaka-u.ac.jp
Tel:06-6879-4636